Current Understanding of Breast Cancer Risk Factors


  • Khodjaeva Dilrukh lkhomovna Department Assistant Bukhara State Medical Institute Bukhara, Uzbekistan


breast cancer, risk factors


Resume. This publication provides an overview of domestic and foreign literature for the period from 2011 to 2020. Risk factors for the development of malignant neoplasms of the mammary glands were analyzed. The role of the following factors is considered: genetic, chronic inflammatory and hyperplastic diseases of the genitals, reproductive function, hormonal and metabolic disorders, frustrating situations, the presence of somatic pathology, ionizing radiation, and previous surgical trauma of the breast. The results of some cohort epidemiological studies of the influence of these factors (both individual and their combinations) on the development of breast cancer are presented. Keywords: ракbreastcancer, факторыrisk factors. Abstract. This review summarizes the factors of potential risk of breast cancer. Much attention was focused on genetic factor, chronic inflammatory and hyperplastic diseases of endometrium, reproductive function, hormonal and metabolic disorders, frustration, somatic pathology, ionizing radiation, before surgery. We discussed the results of some cohort and epidemiological studies of these risk factors (involvement either separate or the joint effect) in breast cancer development.


Aylamazyan E. K. Modern approaches to the prevention of breast cancer in patients with proliferative processes of the reproductive system / / Medical Academic Journal, 2016, vol. 6, No. 3, pp. 16-27. 2.

Artamonov V. V., Lyubchenko L. N., Shabanov M. A. et al. To study the association of polymorphic markers of the CYP 19 and CYP 17 genes with sporadic breast cancer. - 2014. - Vol. 37, No. 6. - pp. 975-982.

Baylyuk E. N., Aylamazyan E. K., Semiglazov V. F., Niauri D. A. Dependence of the state of the mammary gland in patients with uterine fibroids on the volume of surgical intervention on the appendages / / Journal of Obstetrics and Women's Diseases: scientific and practical journal, 2016, vol. 55, No. 1, pp. 8-11.

Science and innovation 4. Barinov V. V., Blumenberg A. G., Bogatyrev V. N. et al. Tumors of the female reproductive system / M. I. Davydov, V. P. Letyagin, V. V. Kuznetsov, Moscow: Meditsinskoeinformatsionnoeagencie, 2017, 376 p.

БеляловаBelyalova N. S., Belyalov F. I. Faktoryriskaiprofilaktikarakarazlichnykhlocalizatsii [Risk factors and prevention of cancer of various localizations]. 2015, vol. 83, No. 12, pp. 20-24.

Berstein L. M.Oncoendocrinology: traditions, modernity and prospects. - St. Petersburg.: Meditsina, 2014, 343 p.

Bulynko S. Therapeutic nutrition for cancerdiseases, Moscow: OOO "Meditsina" (in Russian).Asstsentr", LLC IKTC "Lada", 2016. - 192 p.

Volobuev A. I., Sinshchyn V. A., Malysheva V. A. et al. Results of examination of women with combined benign hyperplastic processes of the mammary glands and genitals / / Obstetrics and Gynecology. - 2013. - No. 5. - pp. 27-31.

Gantsev Sh. Kh. Guide to practical classes in oncology. - Moscow: OOO "Medical Information Agency", 2017. - 416 p.

Gantsev Sh. Kh.,Galeev M. G., Kharipova E. A. Morphological prognostic factors in breast cancer / / Archive of Anatomy, Histology and Embryology. - 2012. - Vol. 121, No. 2-3. - pp. 37-38.

Garin A.M., Bazin I. S. Ten most common malignant tumors, Moscow: Meditsina Publ., 2016, 266 p.

Gurevich G. I., Kargina E. V., Rodionova T. I., Kargina L. V. Combination of thyroid cancer and mastopathy.Everythingisclear .Teratological Congress "Diagnosis and treatment of nodular goiter". - M., 2014. - P. 117-118.

Davydov M. I., Aksel ' E. M. Statistics of malignant neoplasms in Russia and CIS countries in 2014 // Vestnikrontsim. N.N. Blokhina RAMN. -2016. - T. 17, № 3 (pril. 1) - p. 132.

Davydov M. I., Aksel ' E. M. Statistics of malignant neoplasms in Russia and CIS countries, in 2005, ed acad. RAS and RAMS M. I. Davydov and doct. Vestnik RONTs im. N. N. Blokhina RAMS. - 2017. - Vol. 18, No. 2 (appendix 1). - 156 p.

Zaridze D. G. Epidemiology, mechanisms of carcinogenesis and cancer prevention / / Problems of clinical medicine. - 2015. - No. 2. - pp. 10-16.

Zotov A. S. Mastopathies and breast cancer / A. S. Zotov, E. O. Belik. - 4th ed., dop. - Moscow: MEDpress-inform, 2015, pp. 17-18.

Selected lectures on clinical oncology / Edited by V. I. Chissov, S. L.Daryalova, Moscow: Meditsina Publ., 2011, 736 p.

Imyanitov E. N., Hanson K. P. Molecular oncology: clinical aspects. - St. Petersburg.: Meditsina, 2017, 211 p.

Klinicheskaya mammologiya [Clinical mammology]. Current state of the problem ed. E. B. Kampova - Polevoy,S.S. Chistyakova, Moscow: GEOTAR-Media, 2016, 512 p.




How to Cite

lkhomovna, K. D. (2021). Current Understanding of Breast Cancer Risk Factors. International Journal of Culture and Modernity, 6, 31–37. Retrieved from